NeuroGeMM Research Group
Neuro-Genetics and Mouse Models
Head of Research Group: Dr Binnaz YALCIN, PhD, HDR
Tel: +33 3 80 39 66 60
Meet our Group
ORCID : https://orcid.org/0000-0002-1924-6807
Publons : https://publons.com/researcher/2199799/binnaz-yalcin/
Google scholar : https://scholar.google.fr/citations?
Biography : Dr Yalcin have contributed to important aspects of disease genetics using high-throughput genetic, genomic methodologies and mice as genetic models of cognitive disorders. Her ambition has always been to pursue her career in functional and translational disease genetics at the highest level. Dr Yalcin received her D.Phil in 2007 from the University of Oxford under the supervision of Profs Flint and Mott. During her postdoctoral training (2007-2011), she became interested in outbred mice for genetic studies. She discovered the complexity of genomic structure in mice and how it relates to phenotypic variation. In 2011, she secured an EMBO Fellowship allowing her to move to Switzerland. For her own independent career, she obtained an Ambizione Fellowship in 2013 to work on the neurobiology of intellectual disability. She set up her own laboratory in 2016 at the IGBMC (Strasbourg, France) through an international call. One year later, the High Council for the Evaluation of Research and Higher Education scored her team as “excellent to outstanding with great future prospects”. She presented her work at 24 International Conferences of which 8 were under a formal invitation. She has received 14 awards/prizes, the most recent being the International Mary Lyon Award in recognition for an early-stage independent female researcher. To fund her research, she raised and managed a cumulative sum of 2.5 million EUR and employed four PhD students, two postdoctoral fellows and two research assistants (since 2016). In 2019, she secured a tenured INSERM position (Assistant Professor equivalent) after being ranked Major in a national competition. She has 15 years of experience in mouse neurobiology and recently joined the Governance Board of the International Research Consortium for the Corpus Callosum.
Google scholar : https://scholar.google.com/citations?user=LdfxNkAAAAAJ&hl=en
Biography : Dr Collins has been a lecturer at the University of Burgundy-Franche-Comté since 2012. He holds a D.Phil. from the University of Oxford in genetics of diabetes models and completed a two-year postdoctoral fellowship at the Wellcome Centre for Human Genetics working on metabolic syndrome and morbid obesity. After several years as an electrophysiologist in Prof Rorsman’s laboratory at Oxford, he became interested in neurogenetics and joined Dr Yalcin’s team at the time at IGBMC. In 2019, he joined the NeuroGeMM group at GAD Laboratory to investigate mechanisms underlying comorbidities between cognitive disorders and obesity. Dr Collins provides a 196-hour service teaching in cell biology and animal biology for BSc students with additional teachings in neurosciences and genetics for MSc students. He has extensive experience in high-speed neuroanatomical data analysis, statistical analysis, project and database management and imaging technology development.
After a Bachelor’s degree in Biology and Biochemistry at the University of Burgundy-Franche-Comté and a Master’s degree in Neurobiology at Nice Sophia Antipolis University, Charlotte joined the NeuroGeMM group where she is preparing her thesis. Her work is to establish the deregulated neurobiological mechanisms in Cohen Syndrome and decipher the role of VPS13B in the central nervous system with a focus on the hippocampal formation and the corpus callosum.
After obtaining her Bachelor’s degree in Biochemistry and Molecular Biology, Sylvie joined a Master of Nutrition/Health/Foods. Passionate about experimental work, she joined the NeuroGeMM group in 2019 as a Research Assistant. Sylvie is involved in histology, mouse work and in the development of a single-cell method to map higher-order 3D genome organization in the mouse hippocampus.
Axel is preparing for a Master in Biochemistry and Molecular Biology. He joined the NeuroGeMM group in 2021 to undertake a research project on the pathogenesis of TRAPPC10 gene mutation associated with microcephaly.
Adam is preparing for a Master in Biochemistry and Molecular Biology. He joined the NeuroGeMM group in 2021 to undertake a research project on the role of VPS13B in synaptogenesis.
Zineddine is preparing for a Master in Biochemistry and Molecular Biology. He joined the NeuroGeMM group in 2021 to undertake a research project on mouse neuroanatomical features of Mvp::Kctd13 and Kctd13::Mapk3 double knockouts.
Efil Bayam (in collaboration with Dr J. Godin)
Axel Da Costa
Amicie De Pierrefeu
Visiting International students